Monkeypox Diagnostic Providers and Labs


Providers talking to patientFor Clinical and Laboratory Staff

Providers should reference CDC guidance on Clinical Recognition and consult with the NDDoH ((701) 328-2378) if they suspect monkeypox. Clinicians should use standard droplet precautions when assessing all diseases of possible infectious etiology and refer to PPE appropriate for monkeypox for themselves and their staff.

Laboratory Testing 

North Dakota providers who want to test patients for monkeypox should first consult with the North Dakota Department of Health Disease Control Section by calling:

Phone: (701) 328-2378
Toll-Free: (800) 472-2180

Prevention in Health Care Setting 

Patients with suspected or confirmed monkeypox should be placed in a single-person room, with a dedicated bathroom and minimal transfer of patient and personnel in or out of the room. If a patient needs to be transported outside of their room, they should wear a well-fitting mask and have skin lesions covered by a sheet or gown. 

Negative pressure isolation is typically not necessary, although procedures that are likely to aerosolize viral particles (such as intubation or extubation) should be performed in an airborne infection isolation room and/or with PPE appropriate to safeguard all exposed staff to potentially aerosolized particles.

Personal Protective Equipment (PPE)

PPE used by healthcare personnel who enter the patient’s room should include:

  • Gown
  • Gloves
  • Eye protection (i.e., goggles or a face shield that covers the front and sides of the face)
  • NIOSH-approved particulate respirator equipped with N95 filters or higher


Monkeypox illness is typically self-limited and does not require hospitalization. For those that experience severe disease or at high risk for severe disease, medical countermeasures are available for treatment of monkeypox through the strategic national stockpile. Providers must contact NDDoH's Emergency Preparedness Division ((701)328-0707) to procure antiviral treatments. NDDoH will consult with the CDC and arrange delivery of countermeasures.

Treatment Information for Healthcare Professionals

Additional Resources

FAQs for Providers

NDDOH Monkeypox Lunch and Learn Video

Monkeypox Sample Collection and Referral

August 31, HHS Monkeypox Update Presentation Slides | Recording