Canine Brucellosis (Brucella canis)

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Canine Brucellosis (Brucella canis)

Canine brucellosis is an infectious disease caused by Brucella canis (B. canis) bacteria that can infect dogs. It can also infect humans, although the likelihood of this occurring is low. However, those in certain professions are at an increased risk of infection.


Transmission

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Transmission
  • Animal to Person. People who are in close contact with dogs infected with B. canis may be at risk.
    • Infected dogs may intermittently shed the bacteria for the remainder of their lives.
    • People become infected if the bacteria is ingested or enters the body through a break in the skin or direct contact with mucous membranes (i.e., eyes, nose, or mouth). Typically, there is a low risk of infection for pet owners. 

Those at increased risk of infection include: 

  • Dog breeders
  • Veterinary staff
  • Laboratorians in research or diagnostic laboratories 

Severe outcomes can occur, especially in people who have suppressed immune systems or those who are pregnant. People can become sick when they come into contact with 

  • Reproductive fluids
  • Saliva
  • Nasal secretions
  • Milk
  • Blood
  • Urine
  • Feces

People are not able to spread the disease to others through casual contact. It is unknown if lifelong immunity results from infection. Infections can persist for long periods, even years.


Symptoms

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Symptoms

The incubation period is not well understood, but it is thought to range from one week to several months Symptoms may include: 

  • Fever  
  • Sweats
  • Chills
  • Muscle aches
  • Joint pain
  • Severe/persistent headache
  • Swollen lymph nodes
  • Tiredness
  • Loss of appetite
  • Weight loss
  • Vomiting
  • Diarrhea
  • Swollen liver and/or spleen
  • Serious complication involving multiple organs or systems

Diagnosis

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Diagnosis

B. canis infections can be difficult to diagnose. If a medical provider suspects B. canis infection, laboratory testing should include blood cultures. Commercially available screening tests will not detect B. canis. Providers should consult with public health when testing for B. canis.


Treatment

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Treatment

After a diagnosis is made, a health care provider may prescribe antibiotics. 

For more information about the treatment contact your health care provider or visit B. canis | CDC.


Prevention

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Prevention
  • If a dog is diagnosed with B. canis in North Dakota, a permanent quarantine is issued by the North Dakota State Board of Animal Health
    • It is recommended to euthanize to prevent dog-to-dog transmission, human exposures, and the health of the pet; B. canis is a progressive disease that can drastically reduce a dogโ€™s quality of life.
      • If euthanization is declined, the dog must remain in isolation for the remainder of its life and will not be allowed to come into contact with other dogs and people, except for its caretakers.
      • The dogโ€™s caretakers should use appropriate PPE when handling the dogโ€™s bodily fluids and feces.
  • Biosecurity measures should be followed in veterinary clinics, kennels, and grooming facilities, including
    • Proper cleaning and disinfecting of equipment and surfaces.

       


Exclusion Guidance

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Exclusion Guidance

Individuals with B. canis should not be excluded from work, school, or child care unless the general exclusions apply

For additional information about B. canis
contact the North Dakota Department of Health and Human Servicesโ€™, Division of Public Health, at 800.472.2180.

Resources

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Resources
1. Kimberlin, D. W., Barnett, E. D., Lynfield, R., Sawyer, M. H. (2021) Red Book: 2021- Report of the Committee on Infectious Diseases. 31st ed. American Academy of Pediatrics. [Management and Prevention of Infectious Diseases] [122-133]. 
2. Kimberlin, D. W., Barnett, E. D., Lynfield, R., Sawyer, M. H. (2021) Red Book: 2021- Report of the Committee on Infectious Diseases. 31st ed. American Academy of Pediatrics. [Management and Prevention of Infectious Diseases] [238-240]. 
3. Centers for Disease Control and Prevention. (2021, November 2). CDC โ€“ Brucellosis. Centers for Disease Control and Prevention. Retrieved May 26, 2023, from https://www.cdc.gov/brucellosis/index.html 
4. Centers for Disease Control and Prevention. (2012, November 12). CDC โ€“ Brucellosis - Veterinarians. Centers for Disease Control and Prevention. Retrieved June 1, 2023, from https://www.cdc.gov/brucellosis/veterinarians/index.html 
5. National Association of State Public Health Veterinarians. (2012). Public health implications of brucella canis infections in humans [PDF file]. Retrieved from http://www.nasphv.org/Documents/BrucellaCanisInHumans.pdf
 
08/23/24